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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

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Chen-Chen Qin

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Book Open access Aug 2026

TCRTSdesign: End-to-End Co-Design of Antigen-Specific TCR Sequences and Structures

This work introduces TCRTSdesign, a framework that concurrently generates novel TCR sequences with specific binding capabilities to target pMHC molecules and predicts the full-atom structures of the TCR-pMHC complex, while optimizing their binding affinity.

Yang Xiao, Yu Zhao, Fandi Wu et al. · 0 citations
Book Open access Aug 2026

TCRTSdesign: End-to-End Co-Design of Antigen-Specific TCR Sequences and Structures

Designing functional T cell receptors (TCRs) for a given peptide presented by MHC (pMHC) is an emerging yet highly challenging problem in computational immunology. While recent approaches have achieved initial progress, they face two major limitations: (1) the lack of structural information from TCR–pMHC complexes in t...

Yang Xiao, Yu Zhao, Fandi Wu et al. · 0 citations

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