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Cheng-Hao Ho

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Sep 2026

Phosphine-Catalyzed [3 + 2] Annulations of Indole N-Alkynamides with Ynones: Direct Synthesis of Arylidene Spiro-Cyclopentanone Pyrroloquinolinediones.

We report a phosphine-catalyzed [3 + 2] annulation of indole N-alkynamides with ynones, providing efficient access to arylidene spiro-cyclopentanone pyrroloquinolinediones. The reaction proceeds through the in situ generation of a reactive enedione intermediate and exhibits broad substrate scope, high regioselectivity,...

Raghunath Maruti Walunj, Y. Nagare, Cheng-Hao Ho et al. · 0 citations

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