Author

Cheng Huang

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Open access Aug 2026

Lassa fever and Argentine hemorrhagic fever treatment in guinea pigs using broad-spectrum cap-dependent endonuclease inhibitors

ABSTRACT The class Bunyaviricetes encompasses several highly pathogenic viruses that cause lethal hemorrhagic fevers. Due to their limited prevention and treatment options and high pathogenicity, these viruses require handling in biosafety level-4 facilities. Within the bunyaviruses, arenaviruses are particularly notab...

Junki Maruyama, Satoshi Taniguchi, Takeshi Saito et al. · mBio · 0 citations

Review Open access Sep 2026

Lassa Virus—A Persistent and Evolving Threat

Lassa virus (LASV), the most important human pathogen within the Arenaviridae family, causes Lassa fever (LF), an acute hemorrhagic fever disease endemic in West Africa with high case fatality rates, particularly in pregnant women. Currently, there are no licensed vaccines or antivirals approved for clinical use agains...

Meng-Nan Hu, Emily K. Mantlo, Cheng Huang · Microorganisms · 0 citations