Multiscale white- and gray-matter diffusion abnormalities and their associations with serum ammonia in hepatic encephalopathy: a free-water elimination diffusion MRI study.
BACKGROUND Hepatic encephalopathy (HE) involves complex brain edema, but conventional diffusion models may be confounded by extracellular water and cannot readily distinguish tissue-specific abnormalities from fluid-related effects. This study used a free-water elimination (FWE) diffusion tensor imaging framework to ch...