Cheng-Tao Wang

Stereodivergent Synthesis of C-Glycosides from Glycals by Ni-Catalyzed Cross-Hydrocarbonylation of Alkenes.

C-Glycosides always significantly improve the physicochemical properties and pharmacokinetic characteristics of the native O- and N-glycosides and are one of the most powerful strategies for carbohydrate-based drug discovery. However, direct access to C-glycosides with control of stereochemistry from readily available,...