Drug resistance in cancer is shaped not only by tumor-cell-intrinsic mutations but also by spatially organized microenvironmental states. PLA2G2A, encoding group IIA secreted phospholipase A2 (sPLA2-IIA), is usually discussed as an inflammatory lipid enzyme; however, its cancer relevance depends strongly on cellular so...
Ke-Xun Li, Zi-Long Qian, Jian-Zhe Zhang et al.· Cancer Drug Resistance· 0 citations
Esophageal squamous cell carcinoma (ESCC) remains a major cause of cancer-related mortality, and prognosis depends strongly on detection at a curable stage. Endoscopy is central to screening and diagnosis, but subtle flat lesions, operator dependence, cognitive fatigue, lesion-location blind spots, and variability in i...
Jie Mao, Ke-Xun Li, Zi-Long Qian et al.· Frontiers in Artificial Inte...· 0 citations
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