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Cheng-Yang Zhang

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#machine learning Preprint May 2026

CellScientist: From Execution Feedback to Auditable Model-Revision Trajectories for Cellular Perturbation Prediction

This work presents CellScientist, a protocol-constrained workflow that converts execution and validation feedback into auditable model-revision trajectories, and produces both a selected predictor and an inspectable record of its development.

Meng-Ran Li, Bo Li, Jia-Yi Wang et al. · 0 citations
#artificial intelligence Review Sep 2026

See, Measure, and Reason: Learning Visually Grounded Reasoning in Pathology

ASECT improves over its backbone on three external pathology benchmarks covering classification and question answering beyond cellular composition tasks, and improves over its backbone on three external pathology benchmarks covering classification and question answering beyond cellular composition tasks.

Cheng-Yang Zhang, Wen-Chuan Zhang, Bo Li et al. · 0 citations
#machine learning Preprint Sep 2026

Discover, Falsify, Revise: Auditing Input-Use Claims from Source Code to Predictive Contribution in Agent-Discovered Cell Models

AI virtual cells aim to predict cellular responses to specified interventions, yet held-out predictive performance alone does not establish use of the supplied perturbation information. This prediction-claim gap matters in agentic model discovery, where language-model agents generate and revise predictors using score-b...

Meng-Ran Li, Bo Li, Cheng-Yang Zhang et al. · 0 citations
Review Jul 2026

Do Pathology Vision-Language Models Truly See Pathology?

Pathology vision-language models (VLMs) have recently progressed rapidly and are commonly evaluated by answer accuracy on pathology VQA benchmarks. However, we dig into current evaluations and identify three overlooked issues: 1) Visual evidence is not always necessary. For instance, Gemini-3-Pro achieves 53.5% average...

Chengyang Zhang, Wenchuan Zhang, Bo Li et al. · 2 citations

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