Construction of an Activatable Near-Infrared Fluorescent Probe for Rapid Detection of Selenocysteine and Evaluation of Selenium-Supplementation Effect in Mouse Models
In this work, a robust activatable near-infrared (NIR) fluorescent probe (DCP-BS) was designed and synthesized for the highly selective and sensitive detection of selenocysteine (Sec). DCP-BS employs 2,1,3-benzoselenadiazole (BS) as the recognition moiety and utilizes Sec’s higher nucleophilicity compared to biothiol...