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Author

Cheng Zhang

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Open access Jun 2026

Construction of molecular signatures based on the co-expression network of NECSO-related gene TRPM4 and its prognostic value in hepatocellular carcinoma

The TRPM4-centered 11-gene signature provides robust and independent prognostic stratification in HCC by integrating immune, mutational, and single-cell features and serves as a potential tool for prognostic evaluation.

Jun-Ze Chen, Jia-Mei Li, Zhi-Yong Lin et al. · 0 citations
Open access Jul 2026

Single-Cell Dissection of the Immune Microenvironment in Intrahepatic Metastasis of Multifocal Hepatocellular Carcinoma

Findings identify GPNMB-positive macrophages as key metabolic and immune regulatory hubs, suggesting that targeting the GPNMB–prostaglandin E2 axis provides a promising precision therapeutic strategy for intrahepatic metastasis in multifocal hepatocellular carcinoma.

Yuyan Xu, Cheng Zhang, Zhuo-Cheng Ji et al. · 0 citations

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