Open access
Aug 2026
Epigenetic Reactivation of TNFRSF19 Suppresses Mitophagy and Sensitizes Triple‐Negative Breast Cancer to Doxorubicin
ABSTRACT Doxorubicin remains an important component of chemotherapy for triple‐negative breast cancer (TNBC), yet chemoresistance severely limits its clinical efficacy. Here, we identify Tumor necrosis factor receptor superfamily member 19 (TNFRSF19) as an epigenetically silenced gene that critically regulates doxorubi...
Shiyang Liu, Chen-Guang Liu, Wei-Hong Zheng et al.
· Advancement of science · 0 citations