Author

Chengxin Zhang

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Open access Jul 2026

The Role of Cysteine-Rich Protein 2 in Aortic Dissection: Implications for VSMC Phenotypic Modulation—CSRP2 Impedes the Progression of Aortic Dissection

Aortic dissection (AD) is a severe vascular condition marked by abrupt onset, rapid progression, and heightened mortality rates. Vascular smooth muscle cells (VSMCs), the predominant cellular component of the arterial media, are essential for maintaining the structural integrity and functionality of blood vessels. Rece...

Can Liu, Xiangyu Wang, Cheng An et al. · Biomolecules · 0 citations

Open access Aug 2026

Predicting in-hospital mortality after cardiac surgery using machine learning: temporal validation in the MIMIC-IV database

Background Machine learning (ML) models have been increasingly applied to surgical risk prediction; however, their comparative performance and temporal generalizability remain inadequately evaluated. Methods A retrospective cohort study of 9,956 adult patients undergoing coronary artery bypass grafting and/or valve sur...

Jian-Hui Zhou, Chengxin Zhang · Frontiers in Cardiovascular... · 0 citations