Anthraquinone-fused enediynes (AFEs) are a class of microbial natural products with remarkable cytotoxicity and exhibit promising application prospects in tumor therapy. Taking tiancimycins (TNMs) as an example, this class of compounds holds great potential against triple-negative breast and liver cancers. However, the...
This review examines how the two technologies reinforce each other across the OoC lifecycle, surveys progress toward clinical and industrial translation, and considers longer-term paradigms such as digital twins and programmable virtual humans.
Qian Yong, Chun-Yang Chen, Xi-Meng Zhang et al.· International journal of pha...· 2 citations
A multifunctional peptide-based antibacterial hydrogel (PAHG) for treating infected wounds, constructed through the incorporation of Cys-Arg-NH2 (CR)-Ag nanoassemblies into a bioactive matrix with excellent antibacterial activity against Escherichia coli and methicillin-resistant Staphylococcus aureus.
Heng Ge, Wen Yuan, Yulin Sun et al.· Journal of materials chemist...· 0 citations
It is demonstrated that the catechol-nanocellulose/chitosan polymeric hydrogel effectively overcomes adhesion, infection, and oxidative stress barriers in diabetic wound healing, making it a promising candidate for difficult-to-heal chronic ulcers.
