Author

Chengyun Li

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Open access Aug 2026

scRNA‐Seq in Gastric Cancer Reveals Macrophage‐Derived C1q as a Diagnostic Marker

ABSTRACT Tumor‐associated macrophages (TAMs) and the complement system play pivotal roles in reshaping the chronic inflammatory microenvironment and driving malignant transformation. Although C1QA+ TAMs have been identified in multiple tumor types, their role in gastric cancer (GC) remains unexplored. Single‐cell RNA s...

Saisai Gong, Yu-Peng Zhao, Sheng Yang et al. · Cancer Science · 0 citations

Jul 2026

Identification of SLC2A3 as a Downstream Target of METTL1- mediated N7-methylguanosine Modification During MNNG-induced Gastric Carcinogenesis.

INTRODUCTION Methyl-N'-nitro-N-nitrosoguanidine (MNNG) is an environmental carcinogen that induces Gastric Cancer (GC). N7-methylguanosine (m7G) is a prevalent RNA modification closely linked to cancer onset and progression. However, the role of m7G in regulating gene expression during MNNG-induced gastric carcinogenes...

Jia-Xian Li, Jiabei Jian, Wen-Zheng Yuan et al. · Current Medicinal Chemistry · 0 citations