Catalpol ameliorates intervertebral disc degeneration by suppressing NP cell Pyroptosis via the NF-ĸB pathway.
Intervertebral disc degeneration (IDD) is a prevalent degenerative disorder and a leading cause of low back pain. Catalpol (CAT) possesses recognized anti-inflammatory and antioxidant properties and shows therapeutic potential for various inflammatory diseases; however, its role in IDD remains unclear. This study aimed...