Open access
Aug 2026
Dual‐line Genome‐scale CRISPR Screening Enables Robust Target Gene Discovery
It is shown that dual‐line screening can filter cell line‐specific artifacts and improve functional genomic screening for reliable genetic target discovery in insects and under cold stress, this framework identified candidate regulators of cold tolerance.
Zi-Niu Li, Jiao Qiao, Qiu-Yuan Zhang et al.
· Advancement of science · 0 citations