Review
Aug 2026
Targeting the integrated stress response to overcome cancer therapy resistance: From mechanisms to therapeutic opportunities.
The regulatory mechanisms of the ISR in cancer cells and its crosstalk with other oncogenic signaling pathways are outlined and the potential of leveraging ISR-induced cell death pathways to sensitize tumors to therapy and overcome resistance is explored.
Chenliang Zhang, Liping Li, Ting Zhang
· Biochimica et biophysica act... · 0 citations