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Chetna Dureja

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Review Open access Sep 2026

An integrated view of metabolic and physiological regulation of toxin production in Clostridioides difficile

ABSTRACT Clostridioides difficile is a leading cause of antibiotic-associated diarrhea, with pathogenesis driven primarily by the glucosylating toxins TcdA and TcdB. Traditionally, toxin gene expression has been explained through regulation of the pathogenicity locus by global transcriptional regulators that integrate...

Chetna Dureja, Ann M. McKelvey, J. Hurdle · 0 citations

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