Open access
Sep 2026
Unlocking the Alkynyl Bromide Radical Anion With Alternating Current for Inverse Sonogashira C─H Coupling
Carbon–bromine bond cleavage is a fundamental step in many chemical transformations. Over the past two decades, the reductive cleavage of C(Ar)─Br bonds (via a stepwise pathway) and C(alkyl)─Br bonds (via a concerted pathway) has been extensively studied. In contrast, the cleavage of the C(alkynyl)─Br bond remains unre...
Jun-Ya Wang, Xiao-Zhou Wang, Pui Ying Choy et al.
· Advancement of science · 0 citations