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Chi-Liang E Yen

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Open access Jul 2026

TMEM135 deficiency remodels hepatic lipid homeostasis and protein malonylation through a DHA-sensitive lipogenic program buffered by peroxisomal metabolism

These findings identify TMEM135 as a central regulator of hepatic lipid metabolism and uncover a coordinated mechanism linking lipid availability, lipogenesis, and post-translational metabolic regulation.

Ryo Hagimori, Michael Landowski, Siyu Song et al. · 0 citations

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