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Chi-Ping Day

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Open access Sep 2026

A context-dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma.

Acquired resistance to vemurafenib, a BRAFV600E-targeted therapy, remains a major challenge in melanoma. The translation initiation factor eIF6 has been implicated in cancer; however, its role in vemurafenib resistance is poorly understood. We investigated eIF6 using melanoma cell lines with distinct mutational backgro...

G. Kyriakopoulos, Antonia Petropoulou, A. Anastogianni et al. · 0 citations

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