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Author

Chiara Cimmino

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Open access Sep 2026

In Vitro Generation of TGFb- and IL1a-Induced Fibroblast Subtypes for Mechanistic Studies of Extracellular Matrix Composition and Architecture

Purpose In solid cancers, inflammation and viral infections, two main fibroblastic functions have been identified: myofibroblast-like fibroblasts and inflammatory fibroblasts. In the tumour microenvironment (TME), these cancer-associated fibroblast (CAFs) subtypes are known as myCAFs, which generate a stiffe...

Fàtima de la Jara Ortiz, Chiara Cimmino, K. Grech et al. · 0 citations

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