Open access
Aug 2026
Spheroid cultures reveal cancer stem cell enrichment and distinct chemotherapeutic response in triple-negative breast cancer
Three-dimensional cancer spheroids mimic key morphological and biological features of solid tumors, providing a valuable model for evaluating drug responses and novel insight into the mechanisms underlying 3D growth and chemoresistance that may help inform future therapeutic strategies.
Sithumini Sarathchandra, Chiara Fittipaldi, N. A. Alamukii et al.
· BMC Cancer · 0 citations