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Author

Chien-Chi Wu

2 papers indexed here

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Sep 2026

Affinity‐Switchable Fluorescent Probes for Lateral Flow Detection of Small Reactive Molecules and Enzymatic Activities

Lateral flow assays (LFAs) are powerful diagnostic tools for point‐of‐care testing, but their applications are largely constrained by reliance on antibody‐based capture and nanoparticle signal reporters. Here, we present an affinity‐switchable caged‐biotin fluorescent probe strategy (ASBF‐LFA) that expands the dete...

Yu-Teng Hsiao, Yun-Rong Peng, Che-Wei Liu et al. · 0 citations
Open access Aug 2026

Affinity-Activated Protein Switches for Modular and Signal-ON Detection of Small Molecules

A semisynthetic affinity-activated protein switch strategy that enables Signal-ON detection of small molecules across diverse environments, including live cells, Drosophila brain, and lateral flow assays and establishes a generalizable framework for building programmable protein switches with tunable output modes and p...

Chien-Chi Wu, Hsin-Mei Chen, Tzu-Jung Chang et al. · 0 citations

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