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Chih-Yang Huang

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Review Open access Aug 2026

The Role of Mitochondrial ROS in Neoplastic Transformations, Progression and Therapeutic Targeting

This review summarizes the major sources and regulation of mtROS, their involvement in cancer-associated signaling pathways, mitochondrial calcium dynamics, metabolic adaptations, and resistance to anticancer therapies, and discusses current and emerging mitochondrial- targeting strategies aimed at exploiting mtROS sig...

B. Velmurugan, Shu-Hui Lin, Chih-Yang Huang et al. · 0 citations

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