Author

Chol-Hee Jung

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Open access Sep 2026

Integrated signatures define mutational processes in prostate cancer.

Prostate cancer follows a long and heterogeneous disease course with incompletely understood aetiology1. Here we dissect the mutational processes shaping the genomes of 959 donors from the Pan Prostate Cancer Group and assess their clinical relevance. By integrating de novo extracted single-base substitution, insertion...

A. Gruber, A. Olsen, Bárbara Hernando et al. · Nature · 1 citation

Open access Sep 2026

Prenatal exposure to the plasticizer DEHP increases the likelihood of early-life autism and ADHD symptoms through epigenetic programming.

BACKGROUND Growing evidence implicates prenatal exposure to di-(2-ethylhexyl) phthalate (DEHP), a common endocrine-disrupting plasticizer, in the development of autism and attention-deficit/hyperactivity disorder (ADHD). Yet underlying mechanisms remain unclear. METHODS Here, we examined whether cord blood DNA methyl...

S. Tanner, Alex Eisner, Boris Novakovic et al. · i Medicina · 0 citations