Chong-Chong Wu

Gut microbiota–host co-metabolism in sepsis and critical illness: source, compartment, immune state, and host defense

Critical illness can profoundly disturb the intestinal microbiota–metabolite–host immune axis through the combined effects of shock, hypoxia, altered nutritional intake, antimicrobial exposure, organ dysfunction, and impaired epithelial barrier integrity. These changes can reshape microbial metabolic capacity, host co-...

Gut microbiota–host co-metabolism in sepsis and critical illness: source, compartment, immune state, and host defense