Chong-Jing Mu

ApoB-specific CD4+ T cells in atherosclerosis: MHC-II antigen presentation, T cell plasticity, and immune tolerance

Despite intensive lipid-lowering therapy, substantial residual cardiovascular risk persists, and antigen-specific adaptive immunity may contribute to the inflammatory burden that remains after lipid levels are controlled. Apolipoprotein B (ApoB)-containing lipoproteins accumulate in the arterial wall and undergo local...