Activation of alpha-2 adrenoceptors in locus coeruleus alleviates prenatal lipopolysaccharide-induced cognitive deficits in the offspring of rats
The locus coeruleus (LC), the brain’s principal source of norepinephrine, critically regulates cognitive function. While our previous work established that prenatal lipopolysaccharide (LPS) exposure causes cognitive deficits in rat offspring, the underlying mechanisms and potential therapeutic targets remained unknow...