Tetracycline-loaded nanomotors target neutrophil activation and oxidative stress in acute lung injury
Summary Acute lung injury (ALI) has high mortality, underscoring the urgent need for effective therapies. Excessive inflammation, mainly driven by neutrophil activation and caspase-1-mediated IL-1β/IL-18 release, along with oxidative stress, plays a pivotal role in ALI progression. Tetracycline (TH) has shown promise i...