Open access
Jul 2026
DPCGS: a computational framework for linking GWAS to single-cell transcriptomics in complex traits and diseases
Complex traits and diseases arise from the interplay between genetic variation and cellular heterogeneity, making it essential to understand how genetic risk manifests at the cellular level. However, connecting genome-wide association studies (GWAS) to specific cell populations remains challenging due to cellular compl...
Chonghui Liu, Bo Yuan, Baihan Shen et al.
· bioRxiv · 0 citations