Open access
Aug 2026
Effects of cephalexin treatment on DNA replication dynamics in Escherichia coli
In bacteria, DNA replication and chromosome segregation are tightly coordinated with cell division. The replication run-out method, which combines inhibition of transcription initiation by rifampicin with inhibition of cell division by cephalexin, is widely used to analyse replication dynamics by allowing ongoing...
Iren Grigoryan, Dominika Krawiel, Emma L. Dunbar et al.
· BMC Microbiology · 0 citations