Discovery and Characterization of Neuroactive Secondary Metabolites from Acacia sieberiana with Potential Analgesic Properties
Acacia sieberiana (syn. Vachellia sieberiana), widely used in African traditional medicine for pain, was investigated using an ethnopharmacology-guided workflow integrating LC-MS/MS-based metabolomics and molecular networking to prioritize bioactive secondary metabolites. Fractionation of the ethanolic stem bark extrac...