Direct interaction between miR-210-5p and HIF-1α regulates HIF-dependent transcription
Hypoxia-inducible factors (HIFs) coordinate cellular adaptation to oxygen deprivation, yet whether hypoxia-induced microRNAs directly regulate HIF-dependent transcription remains unknown. Here, we identify miR-210-5p as a nuclear hypoxamiR that directly binds HIF-1α and enhances HIF-dependent transcription. Hypoxia ind...