Open access
Jul 2026
The absence of Trim28 in nephron progenitors results in impaired kidney development and function
ABSTRACT The TRIM28 gene encodes a transcriptional regulator involved in a variety of molecular processes. Inactivation of TRIM28 has been linked to the epithelial subtype of Wilms tumor, the most common pediatric renal malignancy. Therefore, TRIM28 may impact early kidney morphogenesis. To investigate its role in neph...
Balázs Pálházi, Alireza Paikari, Greta Clarén et al.
· Development · 0 citations