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Christopher J. Johnson

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Open access Aug 2026

Using CRISPR/Cas9 to investigate the role of candidate human disease gene orthologs in Ciona

The results identify Pgm3 as the most promising candidate for further development as a Ciona-based model of human disease and demonstrate the utility of tissue-specific CRISPR screening for prioritizing candidate disease gene orthologs identified through comparative genomics platforms like Zoogle.

Sabrina A. Hernandez, Christopher J. Johnson, Alberto Stolfi · 0 citations