Author

Christopher J. Ott

h-index 5 View on Semantic Scholar

We have 2 of 15 papers

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

Jul 2026

Systematic Targeting of Protein Complexes with Molecular COUPLrs

Small molecules that modulate protein complexes have transformed cell biology and oncology, yet few chemical starting points exist to probe protein-protein interactions. To expand this space, we developed molecular COUPLrs, elaborated small molecules flanked by two cysteine-reactive warheads. Using CONNECT, an integrat...

Diane Yang, S. Harry, H. Chong et al. · Cancer Discovery · 0 citations

Open access Aug 2026

A Dimeric Protein-RNA Glue Promotes Multivalent eIF4A-RNA Assembly

BisRoc is identified, a dimeric rocaglate ligand that potently and durably suppresses translation and exhibits greater specificity across a cancer cell line panel than the monomeric RocA.

Jie Liu, Megan K. Moore, Kevin Lou et al. · ACS Central Science · 0 citations