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Author

Christopher Jenkins

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Open access Oct 2026

Compact CRISPR-based genetic circuitry using a miniature genome-integrated Cas12m protein

CRISPR-Cas systems can be repurposed as programmable transcription factors, offering a virtually limitless supply of orthogonal regulators for building genetic circuits. However, the commonly used dCas9-based systems place a heavy burden on the host, are slow to release their target, and suffer interference between gui...

Shivang Hina-Nilesh Joshi, Christopher Jenkins, D. Ulaeto et al. · 0 citations

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