This study investigated the lung-targeting characteristics, dose- and time-dependent effects, and safety of a novel engineered adeno-associated virus (AAV) vector, AAV-LungM3. In vitro, mouse primary lung organoids were transduced with AAV-LungM3 at doses of 103, 104, and 105 vector genomes (vg)/cell, and transduction...
Heng-Hai Nie, Juan Du, Xi-Feng Feng et al.· Journal of Visualized Experi...· 0 citations