Chuang-Jun Liu

Chalcone-pyridine/pyrimidine hybrids: promising candidates for anticancer drug development.

Cancer remains a global health challenge with high morbidity and mortality, and the clinical application of conventional anticancer agents is severely limited by issues such as poor selectivity, systemic toxicity, and multidrug resistance. Chalcones, pyridines, and pyrimidines are privileged heterocyclic scaffolds in m...