Concurrent icotinib and definitive radiotherapy followed by detection of an EGFR exon 20 insertion at disease progression in unresectable stage III EGFR S768I-mutant lung adenocarcinoma: a case report
The case of a 55-year-old woman with unresectable stage IIIC lung adenocarcinoma harboring an isolated EGFR S768I mutation suggests that concurrent icotinib and definitive radiotherapy may represent a feasible individualized treatment option for carefully selected patients with unresectable stage III EGFR-mutant NSCLC...