In lung adenocarcinoma (LUAD), DNA methylation-mediated gene silencing may contribute to tumor initiation, progression, and heterogeneity in treatment response. However, the key methyltransferases involved and their therapeutic potential have not been systematically characterized. This study aimed to address three majo...
Lyubo Wang, Gui-Cai Liang, Lei Zhu et al.· Medical Oncology· 0 citations
Oxidative stress, driven by an imbalance between reactive oxygen species (ROS) production and antioxidant defenses, plays a pivotal role in cancer biology. While persistent, moderately elevated ROS levels can promote genomic instability, tumor progression, and immune evasion, excessive ROS accumulation can overwhelm an...
Xu-Dong Feng, Gui-Cai Liang, Jing-Jing Sun et al.· Frontiers in Molecular Biosc...· 0 citations
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