Review
Oct 2026
Non-histone protein lactylation in cancer metastasis: From metabolic reprogramming to therapeutic targeting.
Cancer metastasis remains the leading cause of cancer-related mortality, and tumor metabolic reprogramming, particularly aerobic glycolysis and lactate accumulation, is increasingly recognized as a metastatic driver. Lysine lactylation provides a direct mechanism by which lactate modifies proteins to shape tumor behavi...
Mithu Howlader, A. Akinyemi, Md Rakibul Alam et al.
· Biochemical Pharmacology · 0 citations