Integrated genomic and machine learning analyses identify SPOP as a candidate biomarker associated with tumor-immune features in nasopharyngeal carcinoma.
BACKGROUND The efficacy of immunotherapy in nasopharyngeal carcinoma (NPC) is limited by heterogeneous mechanisms of immune evasion. Identifying robust molecular biomarkers that predict this phenotype is crucial for patient stratification. This study aimed to identify candidate genes derived from a predefined methylati...