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Author

Chunling Yi

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Open access Sep 2026

fp-tools: A Reproducible Platform for ATAC-seq Footprinting and Regulatory Motif Analysis

Background/Objectives: ATAC-seq footprinting can infer transcription-factor (TF) occupancy across the genome at near-base-pair resolution. However, its broad adoption is limited by high computational demands, complex command-line workflows, and fragmented support for bulk data with biological replicates and single-cell...

Yao-Xiang Li, Chun-Ling Yi · 0 citations
Jul 2026

The Multifaceted Roles of the Hippo-Yes-Associated Protein (YAP)/Transcriptional Coactivator with a PDZ-Binding Motif Pathway in Regulating the Tumor Microenvironment.

This work discusses recent advances in understanding how this pathway modulates the immune landscape, cancer-associated fibroblasts, and tumor vasculature and outlines how YAP/TAZ drives fibroblast activation, matrix stiffening, and promotes cancer-associated fibrosis.

Zihao Sui, Ting Wang, Chunling Yi · 0 citations

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