Chun-Miao Wang

The virulent phage vB_KpnP_JYSS5 and its depolymerase Dep11 targeting K57 Klebsiella pneumoniae: characterization and therapeutic potential against biofilm and systemic infection

Klebsiella pneumoniae frequently causes hospital-acquired and community-acquired infections, posing a serious threat to human health. Lytic phages can rapidly propagate within host bacterial cells and release progeny phages, ultimately inducing the death of the host bacteria. K. pneumoniae depolymerases are...