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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Chun Xiao

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Open access Aug 2026

Integrated transcriptomic and proteomic analysis reveals ECM disruption and ALDH1L1-linked metabolic remodeling in klotho-deficient post-infarction heart failure.

BACKGROUND The role of Klotho in heart failure (HF) and its underlying metabolic mechanisms remain unclear. This study investigated how Klotho deficiency affects extracellular matrix (ECM) homeostasis and metabolic regulation in post-myocardial infarction HF (MI-HF), with a focus on aldehyde dehydrogenase 1 family memb...

Bing Zhao, Chun Xiao · 0 citations

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