Author

Cindy V. Ly

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Open access Aug 2026

Characterizing shared and distinctive molecular phenotypes across motor regions in ALS with and without TDP-43 pathology in a veteran cohort

These findings identify senescence-associated molecular states within vulnerable neuronal populations in ALS and support a model in which persistent stress adaptation may permit neuronal survival while contributing to progressive cellular dysfunction.

P. H. Doyle, Shiva Kazempour Dehkordi, Timothy C. Orr et al. · bioRxiv · 0 citations