Author

Claire F. Verschraegen

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Open access Aug 2026

Pre-treatment T-cell Transcriptional Signatures Predict Immunotherapy Outcomes in Melanoma

Immune checkpoint inhibitors (ICIs) have improved outcomes for patients with melanoma and are now the standard of care for high-risk and advanced disease. However, long-term benefits are observed in only around 25% of patients, with significant risk for immune-related adverse events, highlighting the need for predictiv...

Noah Lepola, C. Dravillas, Shannon Gray et al. · Research Square · 0 citations

Open access Aug 2026

DSAI-11 AN OPTIMIZED MACHINE LEARNING MODEL FOR OVERALL SURVIVAL PREDICTION IN BRAIN METASTASIS PATIENTS USING GENOMIC MUTATION AND COPY NUMBER FEATURES

Abstract Background Cancer progression and patient survival are influenced by both tumor-intrinsic and microenvironmental factors, including the ability of tumor cells to disseminate and colonize distant organs. Organ-specific metastases, particularly brain metastases (BM), exhibit distinct tumor–microenvironment inter...

M. I. Ali, Z. Majeed, Peng Li et al. · Neuro-Oncology Advances · 0 citations