Review
Oct 2026
B-140 Performance and Workflow Impact of Automated Image Analysis in High-Volume ANA HEp-2 IIF Screening
Indirect immunofluorescence (IIF) on HEp-2 cells remains the reference standard for ANA screening, providing semi-quantitative titers and clinically relevant fluorescence patterns. Despite its high sensitivity, it lacks specificity, and interpretation is influenced by population characteristics, analytical variab...
Clara Arraes, Rachel Petrola, Lais Masullo
· Clinical Chemistry · 0 citations