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Author

Claudia Campbell

1 paper indexed here

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Open access Sep 2026

Targeting epithelial IFN-I signaling restores barrier integrity in anti-TNF refractory Crohn’s disease

Abstract Background and Aims Type I interferons (IFN-Is) are central regulators of intestinal epithelial homeostasis, yet their role in driving epithelial dysfunction and therapeutic non-response in Crohn’s disease (CD) remains poorly defined. Here, we investigated epithelial tumor necrosis factor (TNF)–IFN-I crosstalk...

Safina Gadeock, Mikayla R. King, D. Polk et al. · 0 citations

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